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脉冲多普勒超声测定肝硬化患者肝静脉频谱与Fibroscan测值关系研究
作者:梁雄波 程小飞 李紫平 
单位:广东省中山市第二人民医院 超声科 广东 中山市 528447 
关键词:肝硬化 多普勒超声 瞬时弹性成像 
分类号:
出版年,卷(期):页码:2014,6(2):24-26
摘要:

摘要:目的 探讨脉冲多普勒超声和瞬时弹性成像(Fibroscan)观察肝硬化患者肝静脉(HV)血流频谱改变的意义。方法 选择乙型肝炎肝硬化患者(130例)和同期健康体检者(80例),使用脉冲多普勒超声测定肝硬化患者肝静脉血流频谱,并将频谱波形分为0型、1型、2型,同时进行Fibroscan检测。结果 肝硬化代偿期与失代偿期患者HV1(%)、HV2(%)、HV1 + HV2(%)(26.74、18.60、45.35、43.18、38.64、81.82)明显高于正常对照组(8.75、0、8.75,P < 0.001),Fibroscan测值(11.80 ± 4.30,17.60 ± 5.73)明显高于正常对照组(4.90 ± 1.36,P < 0.001),而HV0(%)(54.65,18.18)明显低于正常对照组(91.25,P < 0.001)。结论 运用Fibroscan测值以及脉冲多普勒超声测定肝硬化患者肝静脉频谱波形变化,对判断肝硬化程度,选择治疗方案及预后判断具有重要意义,有望成为当前无痛、无创条件下评估肝硬化程度的另一新途径。

Abstract: Objective Analysis how the blood flow frequency change on cirrhosis patients by spectral Doppler ultrasound and Fibroscan. Methods Hepatitis B patients with cirrhosis (130 cases) and healthy physical examination controls (80 cases) were examined, using pulse doppler ultrasonic measurement in hepatic vein blood flow spectrum of patients with liver cirrhosis, and divided pectrum wave form into type 0 and type 1, type 2, Fibroscan tests were used at the same time. Results The numerical value (26.74, 18.60, 45.35, 43.18, 38.64, 81.82) on decompensated and decompensated cirrhosis group HV1 (%), HV2 (%) and HV1 + HV2 (%) are significantly higher than the control group (8.75, 0, 8.75, P < 0.001), the Fibrorscan numerical value (11.80 ± 4.30, 17.60 ± 5.73) significantly higher than the control group (4.90 ± 1.36, P < 0.001), as the HV0 (%) (54.65, 18.18) significantly lower than the control group (91.25, P < 0.001). Conclusions Take advantage of the Fibroscan and the wave form changes, can be meaningful to the cirrhosis evaluation and the therapeutic method choice, also as the predictor of prognosis. It is an another way to evaluate the cirrhosis in a analgesia, noninvasive condition.

基金项目:
广东省中山市科技计划项目(2013A050)
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