Abstract: Tuberculosis is one of widespread infectious diseases in the world today. Isoniazid, rifampicin
and pyrazinamide are still the first line anti-TB drugs recommended by the World Health Organization.
Antituberculosis drug-induced liver injury is a common adverse reaction, which restrict its application, bring
difficulties to the control of tuberculosis. It is very important for the treatment of tuberculosis to investigate
the pathogenesis and interaction of anti-tuberculosis drugs.