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原发性肝癌合并慢性乙型肝炎患者microRNA基因筛选采取外周血的护理

作者：林晓华 1 李优聪 2 张晓霞 3

单位：1.北京大学深圳医院感染性疾病科广东深圳 518000 2.深圳市宝安区妇幼保健院新生儿科广东深圳 518000 3.广州市妇女儿童医疗中心妇产科部体检中心广州 510000

关键词：护理干预原发性肝癌肝炎乙型慢性外周血采取

分类号：

出版年,卷(期):页码：2015,7(4):78-81

摘要：

摘要：目的分析人性化护理在原发性肝癌合并慢性乙型肝炎患者microRNA基因筛选采取外周血的
应用效果，探讨其应用价值。方法选取2011年10月至2015年4月接收的129例进行外周血采取的原发
性肝癌合并慢性乙型肝炎患者为研究对象，采用抽签随机取样法将其分为对照组（65例）和观察组
（64例）。对照组患者在采取外周血进行microRNA基因筛选过程中给予常规护理；观察组在对照组
基础上给予护理干预措施。比较两组采血质量（采血时间、血液报废率）及不良反应发生率；采用
满意度量表，比较两组患者对护理工作的满意度；比较两组护理纠纷和投诉发生率。结果观察组采
血时间为（56.15 ± 7.43）分钟，对照组为（75.36 ± 8.20）分钟，观察组显著低于对照组，差异具有
统计学意义（t = 14.908，P = 0.000）。观察组血液报废率为4.69%，对照组为18.46%，观察组显著低
于对照组，差异具有统计学意义（χ 2 = 5.954，P = 0.014）。观察组不良反应发生率为6.25%，对照组
为21.54%，观察组显著低于对照组，差异具有统计学意义（χ 2 = 6.278，P = 0.011）。观察组护理满
意度为96.88%，对照组为78.46%，观察组显著高于对照组，差异具有统计学意义（χ 2 = 10.064，P =
0.000）。观察组纠纷发生率为3.13%，对照组为26.83%，观察组显著低于对照组，差异具有统计学
意义（χ 2 = 6.775，P = 0.009）。观察组投诉发生率为1.56%，对照组为21.95%，观察组显著低于对照
组，差异具有统计学意义（χ 2 = 6.804，P = 0.009）。结论护理干预措施有助于缩短原发性肝癌合并慢
性乙型肝炎患者microRNA基因筛选患者采血时间，提高采血质量及采血效率，同时降低不良反应发
生率，使护理工作得到了患者肯定，值得临床上推广应用。

Abstract: Objective To analyze the effect of humanized nursing on peripheral blood taken for microRNA
gene screening of primary hepatocellular carcinoma patients combined with chronic hepatitis B, and to discuss
the application value. Methods Total of 129 cases of primary liver cancer complicated with chronic hepatitis
B were selected and taken peripheral blood in Shenzhen hospital, Peking University from October 2011 to
April 2015. All patients were divided into control group (65 cases) and observation group (64 cases) according
to the random sampling method. The control group were given routine nursing care when taken peripheral
blood for microRNA gene screening; The observation group were given nursing intervention on the basis of
the control group. The blood sampling quality (blood collection time and blood scrap rate) and the adverse
reaction rate were compared between the two groups. The satisfaction of nursing work of the two groups were
compared by satisfaction scale, and the incidence rates of nursing disputes and complaints of two groups were
compared . Results The blood sampling time of the observation group [(56.15 ± 7.43) min] was significantly
lower than that of the control group [(75.36 ± 8.20) min], the differences had statistical significance (t = 14.908，
P = 0.000). The blood rejection rate of the observation group (4.69%) was significantly lower than that of the
control group (18.46%), the differences had statistical significance ( χ 2 = 5.954, P = 0.014). The incidence of
adverse reactions of observation group (6.25%) was significantly lower than that of the control group (26.83%),
the differences had statistical significance (χ 2 = 6.278, P = 0.011). Nursing satisfaction of observation group
was 78.46%, the control group was 96.88%, the differences had statistical significance (χ 2 = 10.064, P = 0.000).
The incidence of disputes of the observation group was 3.13%, and the control group was 26.83%, and the
differences had statistical significance (χ 2 = 6.775, P = 0.009). The incidence of complaints of the observation
group was 21.95%, the control group was 1.56%, the differences had statistical significance (χ 2 = 6.804, P =
0.009). Conclusions Nursing intervention is helpful to shorten the time of blood collection for microRNA gene
screening of patients with primary liver cancer complicated with chronic hepatitis B, and improve the quality of
blood collection and blood collection efficiency, and reduce the incidence of adverse reactions, the nursing work
has been affirmed and it is worthy of clinical application.

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