Abstract: Objective To investigate the clinical significance of platelet count and coagulation function indexes in
patients with hepatitis B cirrhosis. Methods The platelet parameters (PLT) and the coagulation indexes (PT, APTT)
of 112 patients with liver cirrhosis and 78 healthy people were detected by auto-counter and auto-blood coagulation
analyzer respectively, and the results were compared. The differences of those indicators between the 38 cases of
liver cirrhosis bleeding and the 74 cases without bleeding were analyzed furtherly. Results Compared with 78 cases
of healthy control group, PLT of 112 patients in liver cirrhosis group decreased evidently; PT and APTT in these
patients were longer than those in the control group, with significant differences between the two groups (P = 0.0062,
P = 0.0093 and P = 0.0088). There were also significant differences in PLT, PT and APTT in the cases of liver
cirrhosis bleeding and without bleeding (P = 0.0098、P = 0.048 and P = 0.016). Conclusion The platelet count
and coagulation indexes can be used as important indexes to determine the damage degree and the prognosis of
hepatic B and liver cirrhosis patients.