Abstract: Non-alcoholic fatty liver disease is a metabolic stress disorder which is closely related to insulin
resistance and genetic susceptibility. As the living standards continue improving, the prevalence has been rising.
Non-alcoholic fatty liver disease can not only cause seriously abnormal liver transaminases, decompensated
cirrhosis, liver failure and so on, but also is associated with cardiovascular disease, type 2 diabetes and metabolic
syndrome, which is a serious threat to the health of people. Therefore, the treatment of non-alcoholic fatty
liver disease causes more and more attention, and the treatment principles include: ①Removal of the cause
and to treat the primary underlying diseases; ②Basic measures of treatment: lifestyle intervention, dietary
modification, exercise therapy and so on; ③To give a supplementary drug therapy varying from person
to person according to different pathologic features; ④For end-stage liver disease, liver transplantation is
recommend. This article will focus on lifestyle interventions, weight loss surgery and drug treatment progress.