Abstract: Objective To analyze the state of hypothyroidism patients misdiagnosed as digestive system
diseases, and to explore the measures of prevention. Methods “Hypothyroidism” was used as the search
term, the literatures from January 1999 to December 2014 were searched from Wanfang Database and China
National Knowledge Infrastructure. Results More than 80% of the articles had the letter “misdiagnose”. The
misdiagnosis cases with digestive symptoms as main clinical manifestation ranked second to cardiovascular
diseases. The misdiagnosis period lasted for several years. Misdiagnosed cases included: chronic viral
hepatitis B, ascites of hepatocirrhosis, constipation and so on. Conclusions Hypothyroidism has a
high misdiagnosis rate. To improve the understanding of diagnostic criteria and high risk group, deepen
understanding that hypothyroidism was concealed and lack of special symptom, and strengthen clinical skills
training were effective measures in reducing misdiagnosis.