Abstract: Objective To investigate the effects and nursing care of compound glycyrrhizin union and polyene
phosphatidylcholine in treatment of children with acute liver injury. Methods Data of 80 children with acute
liver injury from April 2013 to March 2015 in Shengjing Hospital of China Medical University were analyzed
and divided into control group and experimental group according to random number method. All children were
implemented clinical nursing intervention. The control group were treated with polyene phosphatidylcholine and
the experimental group were treated with compound liquorice anhydride combined with phosphatidylcholine.
The efficacy of two groups were compared. Results In the experimental group, 35 cases were cured, 3 cases
improved, the total effective rate was 95%, which was significantly higher than that of control group (85%) (P =
0.04). The satisfaction rate of experimental group was 95% (38 cases), which was significantly higher than
that of the control group (65%) (P = 0.037). There were no significant difference on ALT, AST, A/G and TBil
index (P = 0.053) before treatment. After treatment, the ALT, AST and other indicators in the experimental
group were significantly lower than those of the control group (P < 0.05). After treatment, the A/G and TBil
in the experimental group were significantly higher than those of the control group (P < 0.05). Conclusions
Effect of compound licorice acid anhydride and polyene phosphatidylcholine on pediatric acute liver injury
is ideal, and the implementation of clinical nursing intervention can improve clinical curative effect and it is
worthy promotion.
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