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高校教师脂肪肝与颈动脉粥样硬化相关性分析
作者:康荣芹1   陈红艳 2 
单位:1. 北京农学院校医院 北京 102206 2. 华北电力大学校医院 北京 102206 
关键词:脂肪肝 动脉粥样硬化 超声检查 
分类号:
出版年,卷(期):页码:2016,8(1):100-102
摘要:

摘要:目的 探讨高校教师脂肪肝与颈动脉内中膜层厚度(intima-media thickness,IMT)及颈动脉
血管斑块的关系。方法 选择2010年1月至2014年12月在某校医院门诊行腹部超声检查的脂肪肝患者
97例为脂肪肝组,选择同期门诊行腹部超声检查排除脂肪肝的103例作为非脂肪肝组,超声检测两
组患者的颈动脉IMT和斑块发生情况,同时测量身高、体重,计算体质指数(BMI),空腹检查血
糖(FPG)、血脂等,并对资料进行统计学分析。结果 脂肪肝组BMI、甘油三酯(TG)、总胆固醇
(TC)、FPG、糖化血红蛋白(HbAlc)、颈动脉IMT和粥样斑块检出率均显著高于非脂肪肝组,
差异有统计学意义(P = 0.000);脂肪肝组HDL显著低于非脂肪肝组(t = -2.688,P = 0.008);两组
LDL、UA比较,差异无统计学意义(t = 1.755,1.301;P = 0.081,0.195)。结论 脂肪肝与颈动脉
IMT、颈动脉粥样硬化密切相关。对于腹部超声检查发现脂肪肝的患者应同时行颈动脉超声检查,及
早进行临床干预以减少心脑血管事件的发生。

Abstract: Objective To explore the relationship between fatty liver and carotid artery intimal-media thickness
(IMT) and plaque in college teachers. Methods Total of 97 patients who were diagnosed with fatty liver disease
through abdominal ultrasound from January 2010 to December 2014 were selected as fatty liver group, and
103 cases without fatty liver disease were selected as non fatty liver group. The carotid IMT and plaque were
examined by ultrasound. The height, body weight, BMI, plasma levels of FPG and blood lipid of the patients
were detected and analyzed. Results In fatty liver group, BMI, total cholesterol (TG), total cholesterol (TC),
fasting blood glucose (FPG), glycosylated hemoglobin (HbAlc), carotid IMT and atherosclerotic plaque were
significantly higher than those in non fatty liver group. The difference between the two groups was statistically
significant (P = 0.000). The level of HDL in non fatty liver group was significantly lower than that in fatty
liver group (t = -2.688, P = 0.008), while no significant differences were observed in plasma LDL and UA
between the two groups(t = 1.755, 1.301; P = 0.081, 0.195). Conclusions Fatty liver disease is closely
associated with intimal-medial thickness and carotid atherosclerosis. Patients diagnosed with fatty liver by
abdominal ultrasound should also be performed with carotid artery ultrasound examination to conduct early
clinical intervention and reduce the occurrence of cardiovascular and cerebrovascular events.

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