Abstract: Objective To investigate the clinical value of reticulated platelet and platelet parameter in patients
with liver cirrhosis and its relationship with Child-Pugh. Methods Total of 162 patients with liver cirrhosis
from January 2014 to August 2015 in our hospital were selected as the observation group, of whom Child-Pugh
A grade were 65 cases, Child-Pugh B grade were 56 cases and Child-Pugh C grade were 41 cases. Fifty cases
of healthy controls were selected in the same period. XN-9000 Sysmex automatic blood cell analyzer was
used to detect the network of platelet, platelet and its parameters. Results ①Compared with healthy control
group, the reticulated platelet (RP) and platelet (PLT) values decreased significantly, but the value of immature
platelet fraction (IPF), mean platelet volume (MPV), platelet distribution width (PDW) and platelet-large cell
ratio (P-LCR) increased significantly, the differences were statistically significant (P = 0.001); ②According to
Child-Pugh standard grading display: with Child Pugh grade increasing, the IPF, MPV, PDW and P-LCR value
increased gradually, PLT and RP value decreased gradually and the differences were statistically significant
among the three groups (P = 0.001). Conclusion Reticulated platelet (RP and IPF) and platelet parameter
(PLT, MPV, PDW and P-LCR) can effectively evaluate the degree of liver cirrhosis and can be used as
clinical evaluation and assessment indicators of the severity of cirrhosis, which can provide a reliable basis for
clinicians to develop reasonable treatment and prevention.