中国肝脏病杂志(电子版)

位置：首页 >> 期刊文章

多普勒超声测定乙型肝炎肝硬化患者肾动脉血流参数与Fibroscan测值的相关性分析

作者：程小飞梁雄波熊晓青唐永丽陈萍

单位：中山市第二人民医院影像科广东中山 528447

分类号：

出版年,卷(期):页码：2016,8(2):107-109

摘要：

摘要：目的探讨应用彩色多普勒超声显像仪以及瞬时弹性成像（Fibroscan）观察和分析乙型肝炎肝
硬化患者的肾动脉血流动力学改变的意义。方法选择2011年1月至2015年3月收治的乙型肝炎肝硬化
患者182例，另选健康对照150例，使用彩色超声多普勒显像仪检测肾动脉舒张期最低血流速度（renal
artery diastolic minimum blood flow velocity，RAVdmin）、肾动脉阻力指数（renal artery resistance
index，RARI）和肾动脉搏动指数（renal artery pulsatility index，RAPI）；同时进行Fibroscan检测，
结果以肝硬度（LSM）表示。结果肝硬化患者RARI、RAPI和LSM值分别为0.85 ± 0.11、1.94 ± 0.53
和（25.8 ± 7.65）kPa，显著高于正常对照组的0.56 ± 0.28、0.83 ± 0.08、（7.5 ± 3.1）kPa（t值分别
为11.9477、27.8716、29.4694，P值为0.041、0.039、0.033）；肝硬化患者的RAVdmin为（8.63 ±
1.89）cm/s，显著低于正常对照组的（16.53 ± 2.86）cm/s，（t = 29.0101，P = 0.033）。肝硬化患者
LSM值与RARI和RAPI呈正相关（r值分别为0.64、0.56，P值分别为0.00021、0.00043）。结论利用
Fibroscan测量肝脏硬度以及彩色多普勒超声动态检测乙型肝炎肝硬化患者肾动脉血流动力学变化，对
乙型肝炎肝硬化患者肝肾功能的监测具有重要意义。

Abstract: Objective To explore the relationship between hemodynamic changes of renal artery measured
by color Doppler ultrasound and fibroscan value in patients with hepatitis B cirrhosis. Methods Total of 182
patients with hepatitis B cirrhosis who were admitted to the Second People’s Hospital of Zhongshan from
January 2011 to March 2015 as well as 150 healthy controls were recruited. The mean renal artery diastolic
minimum blood flow velocity (RAVdmin), renal artery resistance index (RARI) and renal artery pulsatility
index (RAPI) were measured by color Doppler ultrasound. Fibroscan was also carried out. Results The RARI,
RAPI, and Fibroscan values of patients with hepatitis B cirrhosis were 0.85 ± 0.11, 1.94 ± 0.53 and (25.8 ±
7.65) kPa, respectively, and they were significantly higher than those of the control group [0.56 ± 0.28, 0.83 ±
0.08 and (7.5 ± 3.1) kPa] (t = 11.9477, 27.8716, 29.4694; P = 0.041, 0.039, 0.033). The RAVdmin of patients
with hepatitis B cirrhosis [(8.63 ± 1.89) cm/s] were significantly lower than that of the control group [(16.53 ±
2.86) cm/s] (t = 29.0101, P = 0.033). The Fibroscan value was positively correlated with RARI and RAPI (r =
0.64, 0.56; P = 0.00021, 0.00043). Conclusion The liver stiffness assessed by Fibroscan and the hemodynamic
changes of the renal artery measured by color Doppler ultrasound are vitally important for evaluating the
severity of patients with hepatitis B cirrhosis.

基金项目：

作者简介：

参考文献：

服务与反馈：

【文章下载】【加入收藏】