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艾灸治疗乙型肝炎肝硬化患者失眠的疗效观察
作者:高婷婷 1 2   胡东胜 2  
单位:1.天津中医药大学 研究生院 天津 300193 2.天津市第二人民医院 肝病科 天津 300100 
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出版年,卷(期):页码:2016,8(2):123-126
摘要:

摘要:目的 观察艾灸百会、涌泉和三阴交等穴位对乙型肝炎肝硬化患者失眠的疗效。方法 选择2014
年9月至2015年1月就诊于天津市第二人民医院肝病科门诊及住院部的42例乙型肝炎肝硬化失眠患
者,将其随机分为治疗组和对照组。治疗组采用艾灸百会、涌泉和三阴交等穴位的方法进行干预,
对照组采用认知行为疗法进行干预。1周为1个疗程,4个疗程后观察疗效。观察治疗前后两组患者
的匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、Child-Pugh等级评分、血清白蛋白
(albumin,ALB)、总胆红素(total bilirubin,TBil)。结果 给予艾灸干预后,治疗组失眠总有效
率为91%,显著优于对照组的76%,差异有统计学意义(Z = -2.12,P = 0.03);治疗后两组PSQI评
分均有改善且治疗组疗效优于对照组(t = -3.69,P = 0.00);治疗组ALB和TBil治疗后均有改善,
Child-Pugh等级评分无改善(t = 1.45,P = 0.06)。结论 艾灸百会、涌泉、三阴交等穴可增强乙型肝
炎肝硬化患者的免疫功能,改善肝功能,优于认知行为疗法,其机制可能与免疫功能的提升可改善
睡眠质量相关。

Abstract: Objective To observe the therapeutic effects of moxibustion at Baihui (GV20), Yongquan (K11)
and Sanynjiao (SP6) on insonmia patients with hepatitis B related liver cirrhosis. Methods Total of 42
insomnia patients with hepatitis B related liver cirrhosis from September 2014 to January 2015 in the Second
People’s Hosiptal of Tianjin were selected and randomly divided into treatment group and control group.
Moxibustion at Baihui (GV20), Yongquan (K11), and Sanyinjiao(SP6) were applied in treatment group, while
congitive behavior therapy was used in the control group. It was designed 1 week as 1 course .The results
were obtained 4 courses later. Pittsburgh sleep quality index (PSQI), albumin (ALB), total bilirubin (TBil)
and Child-Pugh scores were collected. Results The total effective rate in treatment group and control group
were 91.0% and 76.0%, respectively, the difference was statistically significant (Z = -2.12, P = 0.0). After
treatment, PSQI score improved in both groups and the difference was statistically significant (t = -3.69, P =
0.00). Compared with control group, ALB and TBil in treatment group improved significantly, but the Child-
Pugh score had no significant improvement (t = 1.45, P = 0.06). Conclusions Moxibustion at Baihui (GV20),
Yongquan (K11) and Sanyinjiao(SP6) can improve immune function and liver function, and the efficacy was
higher than congitive behavior therapy in treating insonmia patients with hepatitis B related liver cirrhosis.
The possible mechanism could be that the enhanced immune function could improve the sleep quality.

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