Abstract: Clinical studies showed silymarin agents are effective in liver protection in patients with liver
disease and silymarin agents are recommended in several Chinese guidelines in complementary management
of different liver diseases. Yet comprehensive review of data about silymarin agents is needed to provide
specific recommendation in management of different liver diseases. The committee of silymarin therapy in
patients with liver diseases published the consensus on silymarin therapy in patients with liver diseases to
standardize the clinical silymarin therapy in complementary therapy of liver diseases.