Abstract: Nucleos(t)ide analogues (NAs) are potent in inhibiting hepatitis B virus replication and improving
prognosis in most patients with chronic hepatitis B. But primary non-response, suboptimal response, and
relapse may occur in some patients. To optimize the management of NAs experienced patients, the committee
for antiviral therapy in nucleos(t)ide analogues experienced chronic hepatitis B patients published the
consensus on antiviral therapy in nucleos(t)ide analogues experienced chronic hepatitis B patients in 2013.
With more and more evidence in management of these patients in the late 3 years, the committee of antiviral
therapy in nucleos(t)ide analogues experienced chronic hepatitis B patients updated the consensus to provide
the updated recommendation for management NAs experienced patients.
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