Abstract: Non-alcoholic fatty liver disease (NAFLD) is currently considered to be a serious problem to
public health in our country. The mechanism of NAFLD remains unclear and has been a topic at present.
Accumulating evidences have implicated Helicobacter pylori infection as an independent risk factor for the
development of NAFLD. This review summarizes the evolution of the pathogenetic role of Helicobacter
pylori in NAFLD. Thus, eradication of Helicobacter pylori may provide new treatment strategies to halt the
progression of NAFLD.