Abstract: Objective To explore the relationship between liver ultrasonic changes and liver damage in patients
with chronic hepatitis B (CHB). Methods Total of 500 patients with CHB from January 2013 to June 2015
in our hospital were enrolled as the patient group and were divided into mild group (237 cases), moderate
group (183 cases) and severe group (80 cases) according to the severity of abnormal liver function. While,
150 cases of synchronous healthy population were enrolled as the control group. The changes of liver color
ultrasound were observed and analyzed. Results Liver ultrasonography in control group showed that the liver
edge was sharp, liver parenchyma echo was uniform and the largest diameter of hepatic right lobe, Fibroscan
value and liver hemodynamics indexes were normal. Nevertheless, in patient group, the liver edge was blunt,
liver parenchyma echo was thick and uneven, the largest diameter of hepatic right lobe was shrunken and the
Fibroscan value increased. As the damage of liver progressed, the diameter of portal vein, systolicdiastolic
(S/D), resistance index (RI) and hepatic artery systolic or diastolic peak increased, and the velocity of right
portal vein declined. Conclusion The changes of liver ultrasonic can reflect the degree of liver damage in
patients with CHB in some extent, which have important reference values on severity evaluation and clinical
practice.