Abstract: Objective To investigate the influencing factors and nursing experiences of patients who
underwent liver biopsy. Methods Total of 510 patients who underwent liver biopsy from January 2000 to
January 2011 in Guangdong Medical College affiliated to Shenzhen Third People’s Hospital were selected.
Effects of gender, age and whether accompanied by family members on pain, blood pressure, anxiety and
adverse reactions of the patients were compared. The anxiety level was assessed by Zung Self-rating Anxiety
Scale (SAS) measurement, and the degree of pain in the liver area was assessed by the McGill question and
answer classification. Results ①The changes of blood pressure, the degree of pain and the anxiety were more
obvious of female patients than those in male patients, the differences were statistically significant (P ＜ 0.05),
and there was no significant difference in adverse reactions (χ 2 = 1.213，P = 0.271). ②Change of blood
pressure, liver area pain sense, anxiety level and adverse reactions occurred in patients with ages ≥ 40 years
old were more obvious than those of patients with ages ＜ 40 years old, and the differences were statistically
significant (P ＜ 0.05). ③Patients with no family accompanied in the changes of blood pressure, liver
area pain and anxiety level were more obvious than those in patients with family members accompanied,
the differences were statistically significant (P ＜ 0.05), and there was no significant difference in adverse
reactions (χ 2 = 0.332，P = 0.564). Conclusions For women patients, who were older than 40 years old and

without family accompanying, the pain in the liver area, blood pressure changes, anxiety, adverse effects were
more obvious in liver biopsy. For these patients, propaganda, education, psychological intervention, emotional
counseling and full care should be done by the nurse before the operation, and the condition changes of the
patient should be monitored closely.