Abstract: Objective To analyze the effects of devascularization and endoscopic variceal ligation in treatment
of patients with liver cirrhosis and esophageal variceal bleeding. Methods Total of 300 liver cirrhosis patients
with esophageal variceal bleeding in our hospital from February 2013 to February 2015 were randomly selected,
among whom 180 cases were given devascularization and 120 cases were given endoscopic variceal ligation.
The liver function, rebleeding rate and fatality rate of the two groups were observed after treatment for 1 month,
6 months and 1 year. Results The level of TBil in patients treated with devascularization increased significantly
and the highest level was 38 mg/L (t = 3.32, P = 0.021), while the level of ALB decreased. The level of TBil
and ALB had statistical differences between the two groups (P ＜ 0.05). The levels of platelet (PLT) in patients
treated with devascularization increased significantly and showed an increasing trend. The rate of rebleeding
and mortality in patients treated with devascularization were significantly lower than those of patients treated
with ndoscopic variceal ligation (P ＜ 0.05). Conclusions The liver function and ALB level had improvement in
patients treated with devascularization and no improvement in patients treated with endoscopic variceal ligation.
The rebleeding rate and fatality rate of patients treated with devascularization are significantly lower than those
of patients treated with endoscopic variceal ligation.