Abstract: Objectives To assess the prediction value of MELD, Child-Turcotte-Pugh (CTP) and MELDNa
on the mortality of patients with virus-related decompensated cirrhosis during 3 months after discharging
from hospital. Methods Total of 120 patients with virus decompensated cirrhosis in Department of Infectious
Diseases of Renmin Hospital of Wuhan University from January 1 2014 to October 1 2015 were involved
in this study. The mortality during 3 months was obtained and scores of MELD, CTP and MELDNa were
calculated, respectively. The predictive ability of these scoring systems on the early-term outcome in patients
with decompensated cirrhosis were also assessed. Results MELD, CTP and MELDNa scores systems
were significantly different between the non-survival and survival group (z = -6.532, -6.674, -6.399; P <
0.001). MELDNa was the most excellent predictor of 3 months mortality (AUROC = 0.882,P < 0.001)
Conclusions MELD, MELDNa and Child-Turcotte-Pugh score systems were reliable predictors of short-
term outcome in patients with virus-related decompensated cirrhosis. Compared with MELD and CTP
classification, MELDNa could improve predictive ability of early-term mortality. However, data still needs to
be confirmed by large scale trials.
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