Abstract: Objective To investigate the unhealthy lifestyle and its influencing factors of patients with chronic
hepatitis B, and to provide scientific evidence for health education. Methods Self-compiled questionnaire
(including general situation questionnaire, disease related knowledge questionnaire, lifestyle questionnaire
and the generally accepted Medical Coping Modes Questionnaire) were used to survey 479 patients with
chronic hepatitis B in six hospitals of grade two and above in Shandong Province. The influence factors of
unhealthy lifestyle were analyzed by Logistic regression. Results Total of 60.1% patients with CHB had more
unhealthy life style. Logistic regression showed that disease related knowledge, medical coping style, gender,
disease staging, years of anti-HBV treatment and economic pressure were the influence factors of unhealthy
lifestyle of patients with CHB. Conclusions More than half of CHB patients have more unhealthy lifestyle,
and the knowledge-belief-behavior health education model should be used to promote the health of patients
with CHB.