摘要:
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摘要:非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是指除外酒精或其他明确损害
因素所致的以肝细胞内脂肪过度沉积为主要特征的临床病理综合征,其发生发展与胰岛素抵抗、肥胖
和脂质沉积等密切相关。Adropin是近年来新发现的一种蛋白质,因具有调节脂质代谢和维持胰岛素
敏感性的重要作用已引起国内外的重视。本文就adropin的功能及近年来adropin与NAFLD的研究现状
进行综述,为增强NAFLD及其并发症的防治效果提供新思路。
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Abstract: Non-alcoholic fatty liver disease (NAFLD) is a clinical syndrome characterized by excessive
lipid deposition of hepatic cells, which is not caused by alcohol or other specific injury factors. Insulin
resistance, obesity, and lipid deposition are closely related to the occurrence and development of NAFLD.
Adropin, a newly discovered protein in recent years, plays an important role in regulating lipid metabolism
and maintaining insulin sensitivity. In this review, we summarized the function of adropin and the research
progress of adropin in NAFLD, which may provide a new insight into the enhanced diagnosis and treatment
of NAFLD and its complications.
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