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摘要：
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摘要：本文报道1例失代偿期酒精性肝硬化合并大量腹水患者，传统肝细胞肝癌（hepatocellular
carcinoma，HCC）筛查指标甲胎蛋白（alpha fetoprotein，AFP）阴性，但脱-γ-羧基凝血酶原（des-
gamma-carboxy-prothrombin，DCP）升高达正常值的48倍，最终通过影像学确诊为HCC并腹膜转移。
提示DCP在HCC早期筛查中具有重要意义，可弥补AFP在HCC筛查的不足，尤其是酒精性肝病导致的
HCC。
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Abstract: We reported one patients with decompensated alcoholic cirrhosis, whose alpha fetoprotein (AFP),
the traditional screening index of hepatocellular carcinoma (HCC) was negative, but des-gamma-carboxy-
prothrombin (DCP) rose up to 48 times as high as the normal value. Finally, the patients was diagnosed as
HCC with peritoneal carcinomatosis by imaging. The results suggested that DCP is of great significance in
early HCC screening, which can make up for the deficiency of AFP in HCC screening, especially HCC caused
by alcoholic liver disease.
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