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摘要：
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摘要：目的 探讨肝硬化合并感染性休克患者的预后影响因素。方法 以2013年3月至2018年2月内蒙古
自治区人民医院感染科收治的96例失代偿期肝硬化合并感染性休克患者为研究对象，根据患者预后分
为存活组（58例）和病死组（38例）。比较两组患者性别、年龄、感染部位、基础疾病、住院时间、
并发症及生物化学指标的差异，采用多因素Logistic回归分析失代偿期肝硬化合并感染性休克患者预
后的影响因素。结果 存活组和病死组患者肺部感染、住院时间、上消化道出血，ALB、Cr、CRP和
PCT水平差异有统计学意义（P ＜ 0.05）。Logistic多因素回归分析表明，肺部感染、上消化道出血、
Cr ≥ 170 μmol/L、CRP ≥ 35.0 mg/L及PCT ≥ 2 μg/L是失代偿期肝硬化合并感染性休克患者预后的独
立危险因素。结论 失代偿期肝硬化合并感染性休克患者的病死率高，肺部感染、上消化道出血、Cr ≥
170 μmol/L、CRP ≥ 35.0 mg/L和PCT ≥ 2 μg/L是其预后的独立危险因素。
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Abstract: Objective To investigate the prognostic risk factors for liver cirrhosis patients complicated with septic
shock. Methods Total of 96 decompensated cirrhosis patients complicated with septic shock in Department
of Infectious Diseases, Inner Mongolia Autonomous Region People’s Hospital from March 2013 to February
2018 were selected and divided into survival group (58 cases) and death group (38 cases) according to the
prognosis. The sex, age, infection site, underlying diseases, hospital stay, complications, and biochemical
indexes of patients in two groups were compared. Prognostic factors for patients with decompensated cirrhosis
complicated with septic shock were analyzed by multivariate Logistic regression. Results There were significant
differences in pulmonary infection, hospital stay, upper gastrointestinal bleeding, ALB, Cr, CRP and PCT of
patients in two groups (P ＜ 0.05). Multivariate Logistic regression analysis showed that pulmonary infection,
upper gastrointestinal bleeding, Cr ≥ 170 μmol/L, CRP ≥ 35.0 mg/L and PCT ≥ 2 μg/L were independent
risk factors for prognosis of decompensated cirrhosis with septic shock. Conclusions The mortality of
decompensated cirrhosis patients with septic shock was high. Pulmonary infection, upper gastrointestinal
bleeding, Cr ≥ 170 μmol/L, CRP ≥ 35.0 mg/L and PCT ≥ 2 μg/L were independent risk factors for prognosis
of decompensated cirrhosis with septic shock.
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