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经颈静脉肝内门体分流术成功救治慢性肝衰竭患者食管胃静脉曲张破裂大出血后致凝血功能障碍1例
作者:赵莹莹  李贲  李玥  赵红  庄立伟  段英  王笑梅  邢卉春 
单位:首都医科大学附属北京地坛医院 肝病三科 北京 100015 
关键词:肝功能衰竭 慢性 食管胃静脉曲张破裂出血 经颈静脉肝内门体分流 
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出版年,卷(期):页码:2020,12(2):86-88
摘要:
摘要:本例慢性肝衰竭患者因反复消化道食管胃静脉曲张破裂出血,血压偏低,无手术治疗机会,亦 无经济条件进行肝移植。若不能控制出血,患者随时可能因失血过多而死亡。在无其他选择及患者和 家属强烈要求下行经颈静脉肝内门体分流(transjugular intrahepatic portosystemic shunt,TIPS)术,患 者术后凝血酶原时间(prothrombin time,PT)和凝血酶原活动度(prothrombin activity,PTA)低于 检测下限状态持续40 d,经过精心治疗,患者出血停止,肝功能及凝血功能逐渐恢复至出血前,病情 好转出院。现对该例患者进行报道并进行文献复习。
Abstract: The patient with chronic liver failure, who suffered from esophagogastric variceal bleeding during hospitalization along with low blood pressure, neither had opportunities for surgical treatment, nor received the liver transplantation due to economic constraints. If active bleeding persisted, the patient may die from massive bleeding at any moment. At the adamant demand of patient’ s families, we had no alternative but transjugular intrahepatic portosystemic shunt (TIPS) for emergency rescue. Postoperative coagulation dysfunction characterized by value of prothrombin time (PT) and prothrombin activity (PTA) below detection limit lasted for 40 d, after meticulous treatment, the active bleeding never reappeared. Simultaneously, liver function and coagulation function recovered to previous levels and the patient got better and discharged with conditions improved. Now this case was reported and articles were reviewed.
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