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摘要：
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摘要：血清铁蛋白是人体内铁的主要贮存形式，可有效维持机体内铁平衡。病理状态下，铁过载可诱
发氧化应激损伤机制，造成活性氧生成和DNA损伤等，肝脏的铁存储量最大，是铁过载致组织损伤
的主要靶器官。铁蛋白可有效反映体内贮存铁水平，并参与肝脏疾病的发生发展，因此了解铁蛋白的
结构、功能及其与肝脏疾病的关系在提升肝脏疾病诊断、疗效判定及预后分析水平等方面具有重要意
义。
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Abstract: Serum ferritin is the main form of iron storage in human body, which can effectively maintain iron
balance. Under pathological conditions, iron overload can induce oxidative stress injury mechanisms, leading
to active oxygen generation, DNA damage, etc. The liver stores the largest amount of iron, and thus becomes
the main target organ of tissue damage caused by iron overload. Ferritin can effectively respond to the level
of iron stored in the body and participate in the occurrence and development of liver diseases. Therefore, it is
of great significance to understand the structure, function of ferritin and its relationship with liver diseases in
order to improve the level of diagnosis, efficacy evaluation and prognosis analysis of liver diseases.
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