摘要:
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摘要:近年来,药物性肝损伤(drug-induced liver injury,DILI)的发病率逐年增高,目前尚缺乏特
异的临床表现和监测指标,严重者可进展为急性肝衰竭,部分患者血清学指标持续异常而发展为慢性
DILI。现对DILI慢性化相关预测指标及危险因素进行综述,以期对DILI的临床诊治提供帮助。
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Abstract: The incidence of drug-induced liver injury (DILI) has increased year by year. Currently, there
are still no specific clinical manifestations and monitoring indicators. In severe cases, patients may develop
into acute liver failure. A number of patients may develop into chronic DILI with persistent serological
abnormalities. The prediction indexes and risk factors related to chronic DILI were reviewed in order to
support the clinical diagnosis and treatment of DILI.
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