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摘要：
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摘要：肝硬化是我国常见慢性疾病之一，其并发症发病率逐年提升，严重威胁人类健康。胰岛素样生
长因子（insulin-like growth factor，IGF）可抑制肝星状细胞的激活，从而抑制肝纤维化，延缓其向肝
硬化进展。IGF与肝硬化患者Child-Pugh分级和预后密切相关。本文就IGF在肝硬化的作用机制、临床
评估、并发症及对未来诊疗的展望进行综述。
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Abstract: Liver cirrhosis is one of the most common chronic diseases in China, and the incidence of
complications is increasing year by year, which threatens human health seriously. Insulin-like growth factor
(IGF) can inhibit the activation of hepatic stellate cell, thus inhibit liver fibrosis and delay its progression to
liver cirrhosis. IGF is closely related to Child-Pugh grade and prognosis of patients with liver cirrhosis. This
article reviewed the mechanism, clinical evaluation, complications and prospects for future diagnosis and
treatment of IGF in liver cirrhosis.
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