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摘要：
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摘要：系统性红斑狼疮（systemic lupus erythematosus，SLE）作为自身免疫性疾病，
可对全身各器官造成不同程度的损伤，但出现严重肝损伤较为少见。本文现报道1例
以急性肝衰竭为首发症状的SLE病例，通过分析患者血清自身抗体、肝组织病理和其
他临床表现，结合2019年欧洲抗风湿病联盟（European League Against Rheumatism，
EULAR）和美国风湿病学会（American College of Rheumatology，ACR）发布的SLE分
类标准明确诊断。
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Abstract: Systemic lupus erythematosus (SLE), as an autoimmune disease, can cause
different degrees of damage to various organs of the body. However, severe liver damage is
relatively rare. This paper reported a case of SLE with acute liver failure as the first symptom.
The diagnosis was made through the analysis of serum autoantibody detection, liver biopsy
results and other clinical manifestations, combined with the latest classification standard of
systemic lupus erythematosus published by European League Against Rheumatism (EULAR)
and American College of Rheumatology (ACR) in 2019.
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