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摘要：
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摘要：目前代谢相关脂肪性肝病（metabolic associated fatty liver disease，MAFLD）已
累及全球约1/3人口，是世界上最常见的慢性肝脏疾病之一。近年来，随着肥胖和代
谢综合征的流行，MAFLD发病率呈上升趋势，MAFLD相关肝癌患者也日益增多。因
此，明确MAFLD与肝癌间的关系尤为重要。本文从MAFLD相关肝癌的流行病学、发
病机制、与病毒性肝炎的关系、危险因素、临床特点和诊断、防治进行综述，以期为
MAFLD相关肝癌的防治工作提供帮助。
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Abstract: Metabolic associated fatty liver disease (MAFLD) is one of the most common chronic
liver diseases in the world, affecting about 1/3 of the global population at present. In recent years,
with the prevalence of obesity and metabolic syndrome, the incidence of MAFLD has been
gradually on the rise, and the number of patients with MAFLD-related hepatocellular carcinoma
(HCC) is also increasing. Due to the effective prevention and treatment of viral hepatitis, MAFLD
has gradually become an important cause of HCC. Therefore, it is particularly important to identify
the relationship between MAFLD and HCC. This article reviewed the epidemiology, pathogenesis,
relationship with viral hepatitis, risk factors, clinical features, diagnosis, prevention and treatment
of MAFLD-related HCC, in order to provide help for its prevention and treatment.
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