Abstract: Thrombocytopenia caused by chronic hepatitis B is common, medication intervention is often
required to prevent bleeding when platelet count < 30 × 109/L. When the platelet count < 10 × 109/L
indicates that the condition is relatively critical. A case of chronic hepatitis B with a progressive decrease
of platelet count to < 10 × 109/L during diagnosis and treatment was reported. The patient had no
bleeding, the results of bone marrow aspiration showed no abnormalities in bone marrow hematopoiesis
and with the improvement of hepatitis B, the platelet count gradually increased as follows.
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