摘要:
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摘要:随着对自身免疫性肝炎(autoimmune hepatitis,AIH)认识的不断深入,国内报
道发病率呈上升趋势,不再认为是少见疾病。对典型表现的AIH患者可遵循指南进行诊
断与治疗。然而,AIH具有明显的异质性特征,对少部分特殊人群或特殊临床表型的患
者,临床诊治仍面临困难与挑战。临床实践中,尤其应针对患者的特殊情况进行个体
化精准施策。本文基于相关临床最新进展并结合最新指南共识的意见,就如何准确把
握这类特殊临床问题以及实施个体化的处理策略进行综述。
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Abstract: With the deepening understanding of autoimmune hepatitis (AIH), the incidence of
AIH in China are increasing, which is no longer considered as a rare disease. AIH patients with
typical manifestations can be diagnosed and treated according to the guidelines. However, AIH is
characterized by obvious heterogeneity. For a small number of patients with special populations or
special clinical phenotypes, there are still many difficulties and challenges in clinical diagnosis and
treatment. In clinical practice, it is especially emphasized that individualized and precise measures
should be carried out according to the specific conditions of patients. Based on the latest clinical
progress and the consensus opinion of the latest guidelines, this article reviewed how to accurately
grasp such special clinical problems and implement individualized treatment strategies.
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