|
摘要：
|
|
摘要：慢性乙型肝炎（chronic hepatitis B，CHB）临床治愈的研究进展迅速，以聚乙二
醇干扰素（peginterferon，Peg-IFN）为基础的治疗方案是CHB临床治愈的主要方案。
治疗基线和治疗中病毒载量水平及乙型肝炎病毒血清学标志物等指标变化是预测疗效
的重要指标。随着治疗的精细化管理，对CHB临床治愈预测因素的探索取得了一定进
展。本文从宿主及病毒两方面对CHB临床治愈疗效的预测指标进行总结，以期为临床
实践提供参考。
|
|
Abstract: Research on the clinical cure of chronic hepatitis B (CHB) is progressing rapidly,
and the treatment regimen based on pegylated interferon (Peg-IFN) is the main regimen for
the clinical cure of CHB. Changes from baseline, on-treatment viral quantitative levels and
hepatitis B virus serologic markers are important predictors of efficacy. With the requirement
of refined management of treatment, some progress has been made in exploring the predictors
of clinical cure of hepatitis B. This article reviewed and analyzed the indicators related to the
prediction of clinical cure of CHB from both host and viral perspectives, with the expectation
that they would provide a reference for the practice of clinical cure.
|
|
基金项目：
|
|
|
|
作者简介：
|
|
|
|
参考文献：
|
|
|
|
服务与反馈：
|
|
【文章下载】【加入收藏】
|
|
|
|