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非酒精性脂肪肝患者肝功能酶学指标与血脂检测结果相关分析

作者：刘宗英

关键词：非酒精性脂肪肝肝功能血清酶学血脂

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出版年,卷(期):页码：2014,6(2):50-52

摘要：

摘要：目的探讨非酒精性脂肪肝患者肝功能酶学指标与血脂的变化。方法在1383例体检者中，选择经超声诊断的非酒精性脂肪肝患者256例作为非酒精性脂肪肝组，235例无指标异常的健康人群作为对照组，把两组人员肝功能酶学指标和血脂指标结果进行统计学对比分析。结果非酒精性脂肪肝组ALT、AST、GGT明显高于对照组，差异均有显著统计学意义（P均= 0.006）；甘油三脂（TG）、总胆固醇（TC）和低密度脂蛋白胆固醇（LDL-C）亦明显高于对照组，差异有统计学意义（P = 0.027、0.028、0.029），高密度脂蛋白胆固醇（HDL-C）明显低于对照组，差异有统计学意义（P = 0.036）。结论非酒精性脂肪肝患者不仅存在明显的肝功能异常，而且血脂代谢也异常紊乱。

Abstract: Objective To investigate the changes of liver enzymes index and blood lipid in patients with non-alcoholic fatty liver. Methods In a set of 1383 physical examination, 256 cases with non-alcoholic fatty liver were diagnosed by ultrasound as a test group, 235 cases of abnormal indicators of healthy people as a control group. Two indicators comparison with statistical of the results were conducted. Results There was significant difference between the serum ALT, AST and GGT of treatment group and control group.The difference were statistically significant (both P = 0.006). TG, TC and HDL-C were also significantly higher than the control group, with a statistically significant difference (P = 0.027, 0.028, 0.029). HDL-C was significantly lower than the control group. The difference were statistically significant (P = 0.036). Conclusions There were obviously abnormality of serum liver function and abnormal lipid abnormalities disorders with non-alcoholic fatty liver patients.

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