Abstract: Objective To discuss the pregnancy outcomes in women with liver cirrhosis after hepatitis B. Methods Pregnant women with compensated liver cirrhosis after hepatitis B who delivered in Beijing Ditan Hospital were retrospectively collected through the HIS system. According to 1∶3 pairing, the corresponding period pregnant women with chronic HBV infection were collected as control group. The incidence of complications in pregnancy women of the two groups were compared. The development of the neonatus were compared too. Results Totally, 25 cases of pregnant women with compensated liver cirrhosis were collected, 19 cases were given antiviral therapy before pregnancy and two cases started antiviral therapy at the second trimester. The average delivery time of women with liver cirrhosis was (258.92 ± 16.42) days (including 14 cases at 37 weeks of pregnancy and after), and the rate of postpartum hemorrhage was 24%, the differences were significant compared with the control group (P = 0.003, P = 0.000). There were no significant differences in the incidence of gestational diabetes mellitus, postpartum hemorrhage, polyhydramnios, oligohydramnios, meconium staining of the amniotic fluid Ⅲ degrees and hypertensive disorder in pregnancy (P ＞ 0.05). To the infants, it had no significant difference on the rate of congenital abnormality in the two groups (P ＞ 0.05). The rate of neonate asphyxia was 12% in infants whose mother were with liver cirrhosis, which had significant difference with the control group. Conclusions Under antiviral therapy and closely clinical monitoring, the pregnant outcomes in patients with decompensated cirrhosis is good, some of them can full-term delivery. But we should pay attention to the postpartum hemorrhage and neonatal asphyxia.